Advocacy, Science & More.
Hypophosphatasia (HPP) is a rare genetic disorder that affects bone and dental development. It is caused by mutations in the ALPL gene, which codes for the tissue-nonspecific alkaline phosphatase enzyme (TNSALP). TNSALP is involved in the mineralization of bones and teeth, and a deficiency of this enzyme can lead to a wide range of symptoms.... Continue Reading →
Vitamin B6: Patient’s with Hypophosphatasia (HPP) typically have high levels of Vitamin B6 in their blood. The level is not just high, it can be 5 to 6 times higher than the upper limit and because this is very common in HPP patients it is often used as a tool to help when diagnosing HPP.... Continue Reading →
In the realm of biology and medicine, enzymes play a vital role in various physiological processes. Tissue-nonspecific alkaline phosphatase (TNAP) is one such enzyme that holds immense importance in human health and disease. This blog post aims to shed light on the nature of TNAP, its functions, and its significance in maintaining overall well-being. Understanding... Continue Reading →
Introduction: Inflammatory bowel diseases (IBDs) affect millions of people worldwide, and one such condition is ulcerative colitis. This chronic condition can significantly impact a person's quality of life, but with proper understanding and management, individuals can lead fulfilling lives. In this blog post, we will delve into what ulcerative colitis is, explore its causes, discuss... Continue Reading →
Introduction: Ehlers-Danlos Syndrome (EDS) and Hypophosphatasia (HPP) are two distinct medical conditions with their own set of symptoms and complications. However, in some cases, there appears to be an overlap between the two disorders, leading to diagnostic challenges and potential implications for patient management. In this blog post, we will delve into the intersection of... Continue Reading →
In recent years, World Inflammatory Bowel Disease (IBD) Day has emerged as a significant global event that brings attention to the challenges faced by millions of individuals affected by these debilitating conditions. Observed on May 19th each year, this awareness day serves as a catalyst for education, support, and advocacy to improve the lives of... Continue Reading →